Is Nutrivene-D really “megadosing”? Despite what skeptics say, the answer is no — and the science proves it. While RDAs represent the bare minimum to prevent deficiency, Nutrivene-D is formulated to meet the unique biochemical needs of individuals with Down syndrome, all while staying safely below NIH upper limits (ULs). In this article, we break down the difference between recommended, therapeutic, and toxic dosing — and show why Nutrivene-D is strategic, not excessive.